The First CRISPR Gene Therapy Is Here

CRISPR is a powerful gene editing tool, but its uses have been purely scientific until now. In 2023, US and UK drug regulators including the FDA approved Casgevy, a CRISPR/Cas9-based therapy for sickle cell disease and beta-thalassemia. The FDA also approved a similar treatment, Lyfgenia. Here's how they work. Hosted by: Reid Reimers (he/him) ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Adam Brainard, Alex Hackman, Ash, Benjamin Carleski, Bryan Cloer, charles george, Chris Mackey, Chris Peters, Christoph Schwanke, Christopher R Boucher, DrakoEsper, Eric Jensen, Friso, Garrett Galloway, Harrison Mills, J. Copen, Jaap Westera, Jason A Saslow, Jeffrey Mckishen, Jeremy Mattern, Kenny Wilson, Kevin Bealer, Kevin Knupp, Lyndsay Brown, Matt Curls, Michelle Dove, Piya Shedden, Rizwan Kassim, Sam Lutfi ---------- Looking for SciShow elsewhere on the internet? SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/ TikTok: https://www.tiktok.com/@scishow Twitter: http://www.twitter.com/scishow Instagram: http://instagram.com/thescishow Facebook: http://www.facebook.com/scishow #SciShow #science #education #learning #complexly ---------- Sources: https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapies-treat-patients-sickle-cell-disease https://www.gov.uk/government/news/mhra-authorises-world-first-gene-therapy-that-aims-to-cure-sickle-cell-disease-and-transfusion-dependent-thalassemia https://www.ema.europa.eu/en/medicines/human/EPAR/casgevy https://www.statnews.com/2023/12/15/europe-crispr-casgevy-approval-sickle-cell-thalassemia/ https://www.nhlbi.nih.gov/health/sickle-cell-disease https://www.nhlbi.nih.gov/health/sickle-cell-disease/sickle-cell-trait https://www.nhlbi.nih.gov/health/sickle-cell-disease/symptoms https://www.nhlbi.nih.gov/health/sickle-cell-disease/health